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  Vol. 122 No. 1, January 2004 TABLE OF CONTENTS
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Aggressive Primary Orbital Melanoma in a Young White Man With No Predisposing Ocular Features

Arch Ophthalmol. 2004;122:118-121.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Primary orbital melanoma is an exceedingly rare tumor1 that probably develops from congenital rests of neural crest cells in the orbit.2 It represents less than 1% of primary orbital neoplasms and usually occurs in the presence of clinical or histological evidence of ocular melanosis or blue nevus syndrome.2 Although orbital melanoma in general carries a poor prognosis, our case was unusual for its extremely aggressive clinical course that resulted in the death of the patient 6 months after presentation.

Report of a Case

A 40-year-old white man was first seen by us in July 1998 with a painless 3-mm proptosis of the left eye of 6 months' duration. There was no clinical evidence of ocular melanosis or blue nevus syndrome. A computed tomographic scan of the orbits revealed a well-defined intraconal mass that was discrete from the optic nerve and the horizontal rectus muscles (Figure 1). In the following 6 weeks, the . . . [Full Text of this Article]


Histopathological Findings
Exenteration Specimen


Comment
Yvonne M. Delaney, FRCOphth; Susan Hague, FRCOphth; Brendan McDonald, FRCPath
Oxford, England

Corresponding author: Susan Hague, FRCOphth, Radcliffe Infirmary, Oxford Eye Hospital, Woodstock Road, Oxford OX2 6HE, England (e-mail: y.delaney@virgin.net)







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