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Aggressive Primary Orbital Melanoma in a Young White Man With No Predisposing Ocular Features
Arch Ophthalmol. 2004;122:118-121.
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Primary orbital melanoma is an exceedingly rare tumor1 that probably develops from congenital rests of neural crest cells in the orbit.2 It represents less than 1% of primary orbital neoplasms and usually occurs in the presence of clinical or histological evidence of ocular melanosis or blue nevus syndrome.2 Although orbital melanoma in general carries a poor prognosis, our case was unusual for its extremely aggressive clinical course that resulted in the death of the patient 6 months after presentation.
Report of a Case
A 40-year-old white man was first seen by us in July 1998 with a painless 3-mm proptosis of the left eye of 6 months' duration. There was no clinical evidence of ocular melanosis or blue nevus syndrome. A computed tomographic scan of the orbits revealed a well-defined intraconal mass that was discrete from the optic nerve and the horizontal rectus muscles (Figure 1). In the following 6 weeks, the . . . [Full Text of this Article] Histopathological Findings Exenteration Specimen
Comment
Yvonne M. Delaney, FRCOphth;
Susan Hague, FRCOphth;
Brendan McDonald, FRCPath
Oxford, England
Corresponding author: Susan Hague, FRCOphth, Radcliffe Infirmary, Oxford Eye Hospital, Woodstock Road, Oxford OX2 6HE, England (e-mail: y.delaney@virgin.net)
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