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Topical Cyclosporin in the Treatment of Chronic Sarcoidosis of the Conjunctiva
Arch Ophthalmol. 2003;121:1333-1335.
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Sarcoidosis is a multisystem, T-lymphocyte–mediated granulomatous inflammatory process of unknown cause. The clinical spectrum varies in severity from single-organ involvement and self-limiting disease to multisystem inflammation with potential mortality. The characteristic noncaseating granulomatous infiltrations can affect almost any tissue, including conjunctivae.1 The granulomatous inflammation of the conjunctivae in the form of conjunctival nodules resembling follicular conjunctivitis is a common initial finding.2 We describe a patient with chronic conjunctivitis who was subsequently diagnosed as having sarcoidosis and successfully treated with topical cyclosporin.
Report of a Case
A 58-year-old white woman was referred for further management of ocular rosacea and keratoconjunctivitis sicca, which had been refractory to treatment with multiple medications, including oral and topical doxycycline, 1% topical prednisolone acetate, 0.5% ketorolac tromethamine, 0.1% olopatadine hydrochloride, and preservative-free artificial tears for 7 months. Her ocular history was remarkable for primary open-angle glaucoma, for which she underwent a bilateral laser trabeculoplasty 1 year prior to our initial . . . [Full Text of this Article]
Comment
Esen Karamursel Akpek, MD;
Ozge Ilhan-Sarac, MD;
W. Richard Green, MD
Baltimore, Md
Corresponding author and reprints: Esen Karamursel Akpek, MD, Wilmer Eye Institute, 600 N Wolfe St, Maumenee Bldg 321, Baltimore, MD 21287-9238 (e-mail: esakpek@jhmi.edu).
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Br. J. Ophthalmol. 2005;89:1363-1367.
ABSTRACT
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