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  Vol. 121 No. 8, August 2003 TABLE OF CONTENTS
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  Clinicopathologic Reports, Case Reports, and Small Case Series
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Congenital Toxoplasmosis With Unusual Retinal Findings

Arch Ophthalmol. 2003;121:1200-1201.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Toxoplasmosis is the most common cause of infectious retinitis in otherwise healthy individuals.1 In the United States, 70% to 80% of women at childbearing age are at risk of developing a primary infection.2 Infants with congenital toxoplasmosis may or may not have clinical evidence of disease. Active disease is characterized by encephalitis, lymphadenopathy, hepatosplenomegaly, pneumonitis, jaundice, rash, thrombocytopenia with petechiae, and a range of neurological manifestations that include microcephaly and seizures.3 A classic triad of convulsions, intracranial calcifications, and chorioretinitis has been associated with congenital infection with Toxoplasma. The presence of this triad of findings, however, is not necessary to establish the diagnosis. Congenital toxoplasmosis can be made on the basis of serologic evidence (IgG and IgM titers) and central nervous system manifestations. Chorioretinal scarring is the most common ocular manifestation of congenital toxoplasmosis, but occasionally acute chorioretinitis is seen in the early neonatal period.

We report an unusual . . . [Full Text of this Article]

Report of a Case


Comment
Kathryn M. Brady-McCreery, MD; Mohamed A.W. Hussein, MD; Evelyn A. Paysse, MD
Houston, Tex

Corresponding author: Evelyn A. Paysse, MD, Baylor College of Medicine, Texas Children's Hospital, 6621 Fannin St, CC 640.00, Houston, TX 77030 (e-mail: epaysse@bcm.tmc.edu).







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