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  Vol. 121 No. 7, July 2003 TABLE OF CONTENTS
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Microsporidial Stromal Keratitis

Arch Ophthalmol. 2003;121:1045-1047.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Microsporida are spore-forming, obligate eukaryotic protozoan parasites that belong to the phylum Microspora. The ophthalmic manifestations of ocular microsporidiosis exhibit characteristic clinical features depending on the genus involved. With the genus Encephalitozoon, infection is limited to the epithelial cells of the cornea and conjunctiva, producing a diffuse punctate epithelial keratoconjunctivitis. With the genera Nosema and Microsporidium, the infection typically involves the corneal stroma, including the keratocytes.1

To date, only 5 case reports of microsporidial stromal keratitis have been published.2-6 We report an additional case caused by Vittaforma corneae (formerly known as Nosema corneum), which was confirmed by histological analysis and electron microscopy.

Report of a Case

A 65-year-old white man was referred with a 4-month history of progressive redness, pain, and decreased vision in the right eye. The patient denied any history of herpes zoster, vesicular eruptions, trauma, and contact lens wear. Ophthalmic examination revealed a best-corrected visual acuity of 20/40 . . . [Full Text of this Article]


Comment
Corresponding author and reprints: Ramon L. Font, MD, Ophthalmic Pathology Laboratory, Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030 (e-mail: rfont@bcm.tmc.edu).



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Zoonotic Potential of the Microsporidia
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Clin. Microbiol. Rev. 2005;18:423-445.
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Ultrastructural examination of two cases of stromal microsporidial keratitis
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J Med Microbiol 2004;53:775-781.
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