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Arch Ophthalmol. 2003;121:898-903.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The Treatment of Age-Related Macular Degeneration With Photodynamic Therapy (TAP) Study Group^1-2 reports 1 and 2 demonstrated a statistically significant reduction in moderate and severe vision loss in patients with predominantly classic subfoveal choroidal neovascular membranes (CNVMs) secondary to age-related macular degeneration (ARMD) treated with intravenous verteporfin (Visudyne; CIBA Vision Corp, Duluth, Ga) and photodynamic therapy (PDT). Patients were followed up every 3 months after PDT treatment with fluorescein angiography. If leakage was identified from the CNVM, patients underwent repeated treatment with verteporfin PDT.

Verteporfin PDT treatment was also associated with fewer eyes experiencing progression of classic CNVM beyond the area of the lesion identified at baseline. At the 12-month follow-up visit, 46% of the verteporfin-treated eyes vs 71.1% of the placebo-treated eyes had documented growth of the CNVM on fluorescein angiography.^1-2

We describe the clinical course and histopathologic findings in 5 patients with predominantly classic subfoveal CNVM secondary to . . . [Full Text of this Article]

Report of Cases


Histopathologic Findings

Comment
Corresponding author and reprints: Jorge G. Arroyo, MD, Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, 243 Charles St, 12th Floor, Boston, MA 02114 (e-mail: jgarroyo@meei.harvard.edu).

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