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Norman C. Charles, MD
New York, NY

Roger E. Turbin, MD
Newark, NJ

Arch Ophthalmol. 2003;121:412-413.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

IDIOPATHIC ORBITAL inflammation encompasses a spectrum of disorders, ranging from mild and steroid-responsive to severely progressive, therapy-resistant, and blinding. We describe a patient with massive bilateral orbital involvement and intracranial extension.

A 36-year-old black female drug abuser noted progressive bulging and blindness in her left eye over 4 months. Her visual acuity was 20/20 OD and no light perception OS. The left eye was totally immobile, with disc pallor and afferent pupillary defect (Figure 1). Orbital biopsy results disclosed patchy lymphoplasmacytic infiltrates, often perivascular, with prominent fibrosis. No granulomatous or xanthogranulomatous inflammation was present. Acid-fast and fungus stains were negative for organisms. Results of systemic evaluation for Wegener granulomatosis, Erdheim-Chester disease, lymphoma, tuberculosis, and sarcoidosis were negative. Subsequently, oral cyclosporin and prednisone were administered.

Figure appears in full text version. Figure 1. Axial computed tomography shows a diffuse infiltrating mass of the left orbit.

The patient . . . [Full Text of this Article]

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