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Enucleation Following Transpupillary Thermotherapy of Choroidal Melanoma: Clinicopathologic Correlations
Arch Ophthalmol. 2003;121:397-400.
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Transpupillary thermotherapy (TTT) is being used increasingly for the treatment of small and some medium-sized choroidal melanomas.1-3 Although several studies have outlined the complications following TTT, such as tumor recurrence,3 vascular occlusions,4 visual field defects,5 and retinal detachment,2 there are only a few studies dealing with histopathologic findings following TTT.6-8 In this article, we present clinicopathologic correlations in 10 eyes that required enucleation after TTT in an attempt to improve our understanding regarding potential limitations of TTT.
Methods
We prospectively collected data from all patients with a diagnosis of uveal melanoma who were treated with planned TTT at the Ocular Oncology Service at Wills Eye Hospital (Philadelphia, Pa) between January 1995 and September 2001.3 Only those patients who eventually required enucleation formed the basis of the present study. Institutional review board approval was obtained.
Tumor progression was defined as any increase in tumor thickness or basal diameter detected by ophthalmoscopy, fundus . . . [Full Text of this Article]
Results
Comment
Corresponding author: Arun D. Singh, MD, Oncology Service, Wills Eye Hospital, 900 Walnut St, Philadelphia, PA 19107 (e-mail: arunsingh@eyetumors.com).
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FULL TEXT
Extended Follow-up of Small Melanocytic Choroidal Tumors Treated With Transpupillary Thermotherapy.
Win et al.
Arch Ophthalmol 2006;124:503-506.
ABSTRACT
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