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Surgical Removal and Histopathologic Findings of a Subfoveal Neovascular Membrane Associated With Choroidal Osteoma
Arch Ophthalmol. 2003;121:273-276.
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Choroidal osteomas are rare benign tumors that typically arise in young women who are otherwise healthy. Approximately 80% are unilateral, although Gass1 describes patients with unilateral osteomas who later develop bilateral disease. Ophthalmoscopic features include a well-defined, slightly elevated, white-to-cream or orange lesion in the peripapillary or macular choroid. Histopathologically, these tumors are composed of cancellous bone and lie between an altered choriocapillaris and the outer choroidal layers.2-3 There is thinning and atrophy of the overlying retinal pigment epithelium (RPE).
Many patients with choroidal osteomas are asymptomatic because vision in the affected eye may be remarkably well preserved. However, visual loss and metamorphopsia can occur due to geographic changes involving the central fovea or serous and hemorrhagic detachment of the macula; the latter is commonly the result of choroidal neovascularization.
No therapies currently exist to eradicate a choroidal osteoma. The subretinal neovascularization that complicates some cases is sometimes observed without . . . [Full Text of this Article] Report of a Case
Comment
Corresponding author and reprints: Donald J. D'Amico, MD, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114 (e-mail: djdamico@meei.harvard.edu).
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Factors Predictive of Tumor Growth, Tumor Decalcification, Choroidal Neovascularization, and Visual Outcome in 74 Eyes With Choroidal Osteoma
Shields et al.
Arch Ophthalmol 2005;123:1658-1666.
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