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Arch Ophthalmol. 2003;121:1779-1783.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Conjunctival melanoma is a rare tumor of the ocular surface, with an annual incidence of fewer than 5 cases per million residents of the United States and a 10-year mortality rate of about 30%.^1-3 The standard management of conjunctival melanoma consists of local resection, with application of cryotherapy to the resection margins.⁴ There is currently no reliable method of predicting which patients will develop regional lymph node metastasis, although tumor thickness is associated with poorer prognosis and higher likelihood of metastatic disease.⁵ After resection of conjunctival tumors, patients are commonly observed clinically until overt clinical signs of metastasis develop. Once clinically detectable metastatic disease develops, the prognosis is poor.

The regional lymph nodes are thought to be the first site of metastasis for most patients with conjunctival melanoma.^1-3 The reported frequency of regional lymph node metastasis secondary to conjunctival melanoma varies from 26% to 40%.^{2, 6} The histologic status of the . . . [Full Text of this Article]

Report of a Case.


Comment.
Bita Esmaeli, MD
Houston, Tex

David Reifler, MD
Grand Rapids, Mich

Victor G. Prieto, MD, PhD; M. Amir Ahmadi, MD; Lillie Hidaji, BA; Ebrahim Delpassand, MD; Merrick I. Ross, MD
Houston

Corresponding author and reprints: Bita Esmaeli, MD, Ophthalmology Section, Department of Plastic Surgery, Box 443, M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030 (e-mail: besmaeli@mdanderson.org).

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