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Arch Ophthalmol. 2003;121:1643-1646.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Retinoblastoma is the most common primary ocular malignancy of young children, with an incidence of 1:17 000 to 1:34 000 new births. Retinoblastoma is bilateral in about 30% of cases.¹ Although new modalities offer an enhanced chance of eye salvage, in bilateral disease, management often leads to enucleation of the more-involved eye, with more conservative treatment of the better eye. Subsequently, the child is watched carefully for recurrence and for any evidence of central nervous system involvement or other malignancies. The retinoblastoma gene (Rb) is located in the 14 band of the q, or long arm, of chromosome 13. The Rb gene causes cancer when its protein product is absent or dysfunctional.

We describe a child with bilateral retinoblastoma after enucleation of the more-involved eye at 13 months of age, who was diagnosed as having Stargardt disease in the preserved eye at age 10 years. The significant points we wish . . . [Full Text of this Article]

Report of a Case


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Eyal Margalit, MD, PhD; Janet S. Sunness, MD; W. Richard Green, MD; Shalom E. Kelman, MD; Andrew P. Schachat, MD; Dean Fiergang, MD
Baltimore, Md

Rando Allikmets, PhD
New York, NY

Corresponding author and reprints: Janet S. Sunness, MD, Wilmer Eye Institute, 550 N Broadway, Suite 611, Baltimore, MD 21205 (e-mail: jsunness@jhmi.edu).

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