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Limited Wegener Granulomatosis With 40 Years of Follow-up
Arch Ophthalmol. 2003;121:1640-1642.
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Wegener granulomatosis (WG) classically consists of necrotizing granulomatous inflammation of the upper and/or lower respiratory tract; necrotizing granulomatous vasculitis, usually affecting small vessels; and focal segmental glomerulonephritis.1 A limited form occurs, however, in which there is no renal involvement.2-3 We report a case of limited WG with apparent orbital involvement and nearly 40 years of follow-up.
Report of a Case
A 14-year-old white girl had painless swelling of her right upper eyelid and diplopia 1 week after a bout of tonsillitis in 1962. The eyelid swelling originally appeared transiently 2 to 3 months prior to the initial visit and then disappeared completely. The tonsillitis was treated with antibiotics, steroids, and tonsillectomy. Examination showed visual acuity of 20/20 OU, marked ptosis of the right upper eyelid, and a firm, nontender, immobile mass below the supraorbital rim, extending posteriorly.
A general physical examination revealed normal vital signs, lungs, heart, abdomen, and integument. Urinalysis findings were normal. . . . [Full Text of this Article]
Comment
Daniel W. Knoch, BS;
Mark J. Lucarelli, MD;
Richard K. Dortzbach, MD;
Morton E. Smith, MD
Madison, Wis
Corresponding author: Mark J. Lucarelli, MD, Oculoplastics Service, Department of Ophthalmology and Visual Sciences, University of Wisconsin–Madison, F4/348 CSC, 600 Highland Ave, Madison, WI 53792.
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