Adenocarcinoma of the Retinal Pigment Epithelium
Arch Ophthalmol. 2003;121:1481-1483.
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Malignant neoplasms of the retinal pigment epithelium (RPE) are rare. Only a few well-documented cases have been described in the last decades.1-8 Some of these tumors developed in association with chorioretinal scars,7 ocular phthisis,1, 4 or congenital hypertrophy of the RPE.8 In this report we describe an additional case arising from a chorioretinal scar 17 years after the development of a subfoveal neovascular membrane.
Report of a Case
A 37-year-old man was referred to our clinic in 1980 for a progressive loss of vision in his right eye during the preceding months. His visual acuity was counting fingers OD and 20/20 OS. Funduscopy showed a subfoveal hemorrhagic lesion in the right eye, several atrophic chorioretinal scars nasal to the optic disc, and peripapillary atrophy (Figure 1A). Fluorescein angiography revealed a subfoveal neovascular membrane (Figure 1B). We assumed that a histoplasmosis-like lesion (pseudo–presumed ocular histoplasmosis syndrome) had caused the observed changes. No . . . [Full Text of this Article]
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Andres Sommacal, MD
St Gallen, Switzerland
R. Jean Campbell, MD
Rochester, Minn
Horst Helbig, MD
Zürich, Switzerland
Corresponding author: Andres Sommacal, MD, Institute of Pathology, Kantonsspital St Gallen, CH-9007 St Gallen, Switzerland (e-mail: a.sommacal@kssg.ch).
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