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Idiopathic Limbal Squamous Metaplasia
Arch Ophthalmol. 2003;121:1473-1475.
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Squamous metaplasia is an abnormal epithelial differentiation represented on the ocular surface by a spectrum of skin-like changes of conjunctival and corneal epithelium.1-3 This pathologic condition can be observed in a variety of ocular surface disorders, including systemic vitamin A deficiency and cicatricial keratoconjunctivitis.4 We recently encountered a patient with a progressively enlarging limbal epithelial ovoid lesion, who was given a histologic diagnosis of corneal and conjunctival squamous metaplasia of unknown cause. Herein we report this rare case and our successful surgical management of the lesion.
Report of a Case
An otherwise healthy 30-year-old man visited an eye clinic because of mild irritation and discomfort in his left eye. A slitlamp examination revealed a flat temporal ovoid lesion (approximately 4 mm x 6 mm) spanning the cornea and conjunctiva. The patient was treated with a short course of steroid and antibiotic eyedrops without improvement. A conjunctival biopsy was performed. Pathologic testing showed only squamous . . . [Full Text of this Article]
Comment
Akira Kobayashi, MD, PhD;
Ryohei Wajima, MD, PhD;
Kazuhisa Sugiyama, MD, PhD;
Akitaka Nonomura, MD, PhD
Kanazawa, Japan
Andrew J. W. Huang, MD, MPH
Minneapolis, Minn
Corresponding author and reprints: Akira Kobayashi, MD, PhD, Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8641, Japan (e-mail: kobaya@kenroku.kanazawa-u.ac.jp).
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