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An Unusual Case of Leukocoria: Heterotopic Brain Arising From the Retina
Arch Ophthalmol. 2003;121:119-122.
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A newborn infant was seen who had leukocoria, total retinal detachment, and a noncalcified mass in the posterior retina. Retinoblastoma was considered a possibility, and enucleation was performed. Pathologic examination findings revealed heterotopic brain tissue arising from the retina to lead us to conclude that posterior segment heterotopic brain tissue is a rare choristomatous lesion that can present as leukocoria.
Report of a Case
An 8-day-old white male was noted to have leukocoria in the right eye on routine examination at his pediatrician's office. He was referred immediately for ophthalmologic examination. There was no family history of retinoblastoma or childhood eye disease.
On examination, the right eye minimally responded to light. The left eye responded normally to light with a brisk blinking reflex. A right afferent pupillary defect was present. Slitlamp examination of the right eye revealed a thick retrolental white plaque (Figure 1). The horizontal corneal diameter OD was 9.5 mm . . . [Full Text of this Article] Pathologic Findings
Comment
Corresponding author: Evelyn A. Paysse, MD, Baylor College of Medicine, Texas Children's Hospital, 6701 Bates St, CC 640.00, Houston, TX 77030 (e-mail: epaysse@bcm.tmc.edu).
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