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Arch Ophthalmol. 2002;120:1219-1222.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Retinal infection with herpes varicella zoster in patients with acquired immunodeficiency syndrome (AIDS) usually produces multifocal outer retinal whitening that rapidly progresses to confluent, full-thickness retinal necrosis. This form of necrotizing herpetic retinopathy, known as progressive outer retinal necrosis, differs from acute retinal necrosis syndrome principally in the lack of prominent intraocular inflammation.¹ Treatment with intravenous antiviral therapy alone has been associated with a disappointing visual prognosis.² We report the visual outcomes associated with the use of combination systemic and intravitreal antivirals in the management of 7 patients with AIDS with progressive outer retinal necrosis.

Report of Cases

There were 4 men and 3 women with AIDS (mean age, 34.6 years [range, 27-38 years]) (Table 1). Two of the 7 patients had a history of cutaneous varicella-zoster virus infection and 1 had encephalitis. Six of 7 patients had bilateral involvement at the time of the diagnosis of retinitis, and the remaining . . . [Full Text of this Article]

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Corresponding author and reprints: Janet L. Davis, MD, Bascom Palmer Eye Institute, PO Box 016880, Miami, FL 33101.

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