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Arch Ophthalmol. 2002;120:1087-1090.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A 27-year-old woman developed malignant orbitoconjunctival melanoma in her left eye 21 years after treatment of a left orbital embryonal sarcoma with systemic chemotherapy and radiation therapy to the orbit. The coexistence of these 2 malignancies in the same orbit is very rare. It may be coincidental, but a genetic predisposition or late adverse effects of childhood cancer treatments cannot be excluded.

Second malignant tumors can occur in patients treated for retinoblastoma during childhood,¹ but other multiple ophthalmic malignancies in the same patient are a very rare occurrence. We report the case of a patient who had 2 distinct tumors involving her left orbit. A childhood sarcoma was followed 21 years later by a malignant melanoma.

Report of a Case

In 1971, a 6-year-old girl developed a tumor in her left orbit. A specimen from an incisional biopsy of the mass showed evidence of embryonal sarcoma (Figure 1 A and B). The patient . . . [Full Text of this Article]

Comment
Corresponding author and reprints: Livia Lumbroso, MD, Institut Curie, 26 Rue d'Ulm, 75005 Paris, France (e-mail: livia.lumbroso@curie.net).

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