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Arch Ophthalmol. 2002;120:978-979.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Langerhans cell histiocytosis is an uncommon, multisystem disease with a clinical spectrum that includes benign unifocal disease (eosinophilic granuloma), chronic multifocal disease (Hand-Schüller-Christian disease), and acute or subacute fatal disseminated disease (Letterer-Siwe disease).¹ It accounts for 1% to 7% of biopsied orbital tumors.² Eosinophilic granuloma is the most common variant of Langerhans cell histiocytosis, with approximately 20% of cases affecting the orbital area.² When it occurs in the orbit, it is usually unilateral and localized. We are unaware of a previously reported case of eosinophilic granuloma with bilateral orbital involvement, and a computerized literature search using Medline disclosed no other examples. We herein report a case of eosinophilic granuloma that exhibited sequential bilateral orbital involvement.

Report of a Case

In November 1988, a 5-year-old otherwise healthy boy was referred to us for evaluation of left eyelid swelling and proptosis that had developed over 1 month (Figure 1A). He had been diagnosed elsewhere . . . [Full Text of this Article]

Comment
Corresponding author: Carol L. Shields, MD, Oncology Service, Wills Eye Hospital, 900 Walnut St, Philadelphia, PA 19107.