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Arch Ophthalmol. 2002;120:659-661.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Myelination of the anterior visual pathways begins centrally at the lateral geniculate body and is completed at term. This process normally terminates at the lamina cribrosa, but it occasionally may extend into and beyond the peripapillary retinal nerve fiber layer. Congenital retinal myelination is not uncommon, occurring in 0.3% to 0.6% of the population as an isolated developmental anomaly, or rarely as part of a generalized disorder, such as the Goltz-Gorlin syndrome, or the syndrome of anisometropia high myopia, and amblyopia.¹ Although recent evidence suggests that the retinal myelination may progress in such cases,² acquired retinal myelination is exceptionally rare.³

We describe 2 cases in which myelinated retinal nerve fibers appeared in children with neurofibromatosis 1 (NF1) and optic nerve glioma. In both cases, spontaneous improvement in visual function preceded the retinal myelination.

Report of Cases

Case 1

An 8-year-old boy was referred to us with reduced vision and optic disc swelling in the right . . . [Full Text of this Article]

Case 2

Comment

Corresponding author and reprints: John S. Elston, BSc, MD, Radcliffe Infirmary, Oxford Eye Hospital, Woodstock Road, Oxford OX2 6HE, England (e-mail: Mary.Spearman@orh.anglox.nhs.uk).