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The Effect of Transpupillary Thermotherapy on the Human Macula
Arch Ophthalmol. 2002;120:648-652.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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INTRODUCTION
Transpupillary thermotherapy (TTT) was introduced by investigators from
the Netherlands in 1995 as an alternative treatment for choroidal melanoma.1-2 Since that time, TTT has been
used to treat small choroidal melanomas, and preliminary results indicating
that TTT can control small melanomas with follow-up of 5 or more years have
been published.3-4 However,
localized retinal destruction, vascular occlusions, and nerve fiber bundle
defects are commonly associated with effective treatment of small melanomas
with TTT. Despite these observed retinal complications, some investigators
have recently reported that TTT, using the same laser intensity to treat choroidal
melanoma, may successfully treat occult subfoveal choroidal neovascularizations
in patients with age-related macular degeneration without observing deleterious
retinal complications.5 The encouraging
results in pilot studies with TTT in the management of occult choroidal neovascular
membranes has led to the development of a multicenter prospective randomized
clinical trial (Transpupillary Thermotherapy [TTT] of Occult Subfoveal Choroidal
Neovascularization in Patients . . . [Full Text of this Article]
Report of a Case
Histopathologic Findings
Comment
Corrresponding author and reprints: Dennis M. Robertson, MD, Department
of Ophthalmology, Mayo Clinic, Rochester, MN 55905 (e-mail: robertson.dennis@mayo.edu).
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