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Cytomegalovirus Retinitis in Patients With Good Syndrome
Arch Ophthalmol. 2002;120:510-512.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Hypogammaglobulinemia and secondary systemic opportunistic infections
are recognized associations in patients with thymoma,1
and the simultaneous occurrence of thymoma and hypogammaglobulinemia is referred
to as Good syndrome.2
We report herein the presentation, clinical course, and outcome of 2
consecutive patients with vitreous biopsy–proved cytomegalovirus (CMV)
retinitis associated with thymoma and immunodeficiency but with no evidence
of other systemic CMV infection.
Report of Cases
Case 1
A 45-year-old woman was referred to Moorfields Eye Hospital, London,
England, in November 1998 with a 2-month history of bilateral posterior uveitis
that was not responding to topical treatment. The patient had no history of
ocular disease, and her medical history included a thymoma treated by excision
and postoperative radiotherapy in 1996, myasthenia gravis (positive acetylcholine
receptor antibody), vasculitis (p–anti-neutrophil cytoplasmic antibody
positive) with mild renal impairment, and recurrent chest infections. She
also had had a recent episode of chicken pox before the onset of ocular symptoms.
The patient . . . [Full Text of this Article] Case 2
Comment
Corresponding author and reprints: Susan Lightman, PhD, FRCP, FRCOphth,
FMedSci, Moorfields Eye Hospital, City Road, London EC1V 2PD, England (e-mail: s.lightman@ucl.ac.uk).
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Cytomegalovirus retinitis in Good syndrome: case report and review of literature
Popiela et al.
BMJ Case Reports 2009;2009:bcr0220091576-bcr0220091576.
ABSTRACT
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