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Congenital Mydriasis, Failure of Accommodation, and Patent Ductus Arteriosus
Arch Ophthalmol. 2002;120:509-510.
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Congenital mydriasis is a very rare abnormality that occurs in combination
with a failure of accommodation. Herein we describe 2 patients in whom these
ocular defects are associated with patent ductus arteriosus (PDA).
Report of Cases
Case 1
This 15-week-old infant was first seen by us 2 weeks after she had undergone
surgery for a large PDA.1 Her parents had
observed the dilated pupils since birth. The photographically measured diameter
of the round pupils was 6.5 mm. They were not reactive to light, to an eyelid
closure effort, or to the administration of up to a 1% concentration of pilocarpine
eyedrops. Streak retinoscopy revealed a refraction of OD +3.0 diopter sphere
(D sph) and OS +2.5 D sph that remained uninfluenced by topical application
of pilocarpine. Apart from the lack of accommodation and pupillary constriction,
all ocular findings were normal. No other pupillary abnormalities were known
in the family. The infant was given spectacles to . . . [Full Text of this Article] Case 2 Comment
Corresponding author: Michael H. Gräf, MD, Department of Strabismology
and Neuro-ophthalmology, University of Giessen, Friedrichstrasse 18, D-35385
Giessen (e-mail: michael.h.graef@augen.med.uni-giessen.de).
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