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Calcium Precipitation on the Optical Surfaces of a Foldable Intraocular Lens: A Clinicopathological Correlation
Arch Ophthalmol. 2002;120:391-393.
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An intraocular lens (IOL) (Hydroview; Bausch & Lomb, Rochester,
NY) developed late postoperative opacification of its optical surface, causing
significant visual symptoms that required explantation. The lens was processed
in our laboratory, and the lens optic, composed of a hydrophilic acrylic polymer,
was stained with alizarin red and the von Kossa stain for calcium. The lens
also underwent scanning electron microscopy and energy dispersive x-ray spectroscopy
of its anterior optical surface. These analyses revealed that the opacity
was caused by deposition of calcium phosphate on the lens surface. This process
appeared to be dystrophic calcification of unknown cause.
Recent reports of IOL calcification have raised concerns regarding the
long-term biocompatibility of 2 modern hydrophilic acrylic foldable lenses:
the Bausch & Lomb Hydroview IOL and the Medical Developmental Research
(Clearwater, Fla) SC60B-OUV.1-3
In this study, we describe the typical appearance of late postoperative opacification
of the former lens with pathological confirmation . . . [Full Text of this Article] Report of a Case
Pathologic Findings
Comment
Corresponding author and reprints: Liliana Werner, MD, PhD, Department
of Ophthalmology, Storm Eye Institute, Medical University of South Carolina,
167 Ashley Ave, PO Box 250676, Charleston, SC 29425-5536 (e-mail: wernerl@musc.edu).
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