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Endogenous Nocardia asteroides Endophthalmitis
Arch Ophthalmol. 2002;120:210-213.
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Nocardia asteroides, a Gram-positive, aerobic,
soil-borne bacterium, is a cause of opportunistic infections in immunocompromised
patients, particularly those with lymphoreticular neoplasms, long-term pulmonary
disorders, and long-term steroid use. The organism is usually inhaled and
may cause localized or disseminated infections. A predilection for its spread
to the brain and soft tissues has been noted. Suppurative necrosis and abscess
formation is the pathologic hallmark. Nocardia is
distinguished by beaded, branching, filamentous growth in purulent exudate
and tissue sections.
Ocular involvement by Nocardia is very rare,
with approximately 30 cases of intraocular nocardial infection reported in
the literature.1-4
Optimal therapeutic regimens are not established. Only 2 reports detail experiences
with intravitreal antibiotics.5 We report
our experience with a case of endogenous N asteroides
endophthalmitis treated with vitrectomy and intraocular and systemic antibiotics,
and for which a diagnostic subretinal biopsy was performed.
Report of a Case
A 69-year old man was admitted to our hospital with . . . [Full Text of this Article]
Comment
Corresponding author: W. Richard Green, MD, Eye Pathology Laboratory,
The Johns Hopkins Hospital, Maumenee 427, 600 N Wolfe St, Baltimore, MD 21287.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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FULL TEXT
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Yu et al.
Am. J. Neuroradiol. 2005;26:1220-1222.
ABSTRACT
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