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Conjunctival Papillomas Caused by Human Papillomavirus Type 33
Arch Ophthalmol. 2002;120:202-204.
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Conjunctival papillomas are associated with human papillomavirus (HPV) infection. In children, the lesions are typically manifestations of an infection acquired during delivery.1 In adults, conjunctival papillomas are most likely venereal and are often associated with anogenital lesions.2 Papillomas due to HPV more frequently progress to malignancy in patients with the human immunodeficiency virus (HIV) infection.3 Human papillomavirus types 6, 11, 16, and 18 have been identified in benign and malignant conjunctival lesions using various antigen and DNA detection techniques.2 For the first time, to our knowledge, we report the finding of HPV type 33 in conjunctival papillomas excised from an HIV-positive patient.
Report of a Case
A 34-year-old HIV-positive man complained of bilateral conjunctival lesions of 4 years' duration. Ten years earlier, he was diagnosed as having HIV after developing pneumocystis pneumonia, a Mycobacterium avium-intracellulare infection, and perianal HPV condylomata acuminata. While receiving highly active antiretroviral therapy (HAART), including indinavir sulfate, nevirapine, and combivir, . . . [Full Text of this Article] Comment
Corresponding author and reprints: Dr Buggage, National Eye Institute, National Institutes of Health, 10 Center Dr, Bldg 10, Room 10N112, Bethesda, MD 20892-1857 (e-mail: BuggageR@intra.nei.nih.gov).
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