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Diffuse Hyperplasia of Intratarsal Ectopic Lacrimal Gland Tissue
Arch Ophthalmol. 2002;120:1748-1752.
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INTRODUCTION
Diffuse bilateral ectopia of lacrimal gland tissue in the tarsal plate has not been recorded previously, to our knowledge. This abnormality was studied in tissue removed from a middle-aged female patient who had bilateral nongranulomatous conjunctivitis and superficial punctate keratopathy. In addition, the patient had microcore myopathy, hypertension, and brittle diabetes mellitus. Clinical investigation revealed surface irregularities in the tarsal plate, and morphologic studies demonstrated large ectopic glands throughout the tarsal plate. Chronic inflammatory cell infiltration was present in the periacinal fibrous tissue, and this progressed to fibrofatty replacement of the glandular tissue. Dilatation of the ductules suggested that blockage of the acinar secretions led to, or was caused by, chronic inflammation in the overlying conjunctival stroma. The symptoms were relieved after excision of both tarsal plates.
Ectopic lacrimal glands on the bulbar conjunctiva within the uveal tract and on the surface of the cornea are a well-recognized source of . . . [Full Text of this Article]
Report of a Case
Comment
Corresponding author: William R. Lee, MD, Tennent Institute of Ophthalmology, Gartnavel General Hospital, 1053 Great Western Rd, Glasgow G12 OYN Scotland (e-mail: wrl1v@clinmed.gla.ac.uk).
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ABSTRACT
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