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Arch Ophthalmol. 2002;120:1379-1383.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

To our knowledge, there have been no reports of transmission of a systemic malignancy from a donor to a recipient by corneal transplantation. Known cases of transmission of disease by transplanted corneal tissue have involved infectious agents^1-14 and 1 case of intraocular tumor.¹⁵ Corneal tissue from donors who have died of malignancy (with the exception of leukemia, lymphoma, and retinoblastoma) has been considered safe for transplantation.^15-19 In contrast, there have been many reports of transmission of systemic malignancy from donor to recipient by solid organ transplantation. The donor origin of one case of tumor transmission by solid organ transplantation was proven conclusively by DNA typing.²⁰ We report the first known instance, to our knowledge, of transmission of a systemic malignancy by corneal transplantation, proven by DNA analyses.

Report of a Case

A 22-year-old man sought treatment in June 1992 because of a 2-week history of slight irritation of his right eye and an area . . . [Full Text of this Article]

Comment
Corresponding author and reprints: Phillip J. Polkinghorne, FRCOphth, Department of Ophthalmology, Auckland Hospital, Private Bag 92024, Auckland, New Zealand (e-mail: philip@pjpolk.co.nz).

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