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Arch Ophthalmol. 2002;120:87-88.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Multiple myeloma is a malignancy of the immune system that infrequently involves the eye. Cysts of the ciliary body and retinal vascular lesions represent the most common ocular manifestations in myeloma patients.¹ This report documents the first case of anterior chamber infiltration–simulating hypopyon (pseudohypopyon) in multiple myeloma.

Report of a Case

A 72-year-old white man was referred by his hematologists for anterior segment evaluation. Hyperemia and soreness of his left eye, accompanied by blurred vision, had been noted over the preceding 3 weeks. The patient had been diagnosed with multiple myeloma 2 months previously following prolonged fatigue, acute renal insufficiency, and high levels of serum calcium and IgG. Subsequently, he received 3 courses of vincristine sulfate, doxorubicin hydrochloride, and methylprednisolone (VAMP) chemotherapy, which resulted in considerable decrease of the paraprotein (IgG). His ocular symptoms developed 2 weeks after the last course of chemotherapy, while he was taking oral amitriptyline hydrochloride, ciprofloxacin hydrochloride, and acyclovir.

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Corresponding author and reprints: Paris G. Tranos, ICO, Department of Ophthalmology, Royal Free Hospital Medical School, Pond Street, London NW3 2QG, England (e-mail: ptranos@hotmail.com).