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Interferon-Associated Retinopathy and Cystoid Macular Edema
Arch Ophthalmol. 2001;119:1077-1079.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Many cases of interferon-associated retinopathy have been reported since
the first case in 1990.1 This disease, characterized
by retinal hemorrhage and cotton-wool spots, has a good prognosis.2-3 We describe the first patient
with interferon-associated retinopathy with decreased vision due to bilateral
cystoid macular edema (CME).
Report of a Case
On February 4, 1999, a 24-year-old man with chronic, active hepatitis
C began treatment with interferon beta at a daily dose of 4 x 106 U for 9 weeks. His corrected visual acuity was 20/20 OU and no abnormal
fundus findings were noted in either eye before treatment. About 1 month later,
the platelet count decreased from 350 x 109/L to 160 x
109/L and the triglyceride level increased markedly from 1.26 to
4.73 mmol/L (112-419 mg/dL). The patient also developed proteinuria and hypoalbuminemia
(serum albumin level decreased from 0.039 to 0.023 g/L). Three days before
the end of treatment, many cotton-wool spots . . . [Full Text of this Article]
Comment
Corresponding author and reprints: Tomohiro Ikeda, MD, Department
of Ophthalmology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya-shi,
Hyogo 663-8501, Japan (e-mail: tikeda@a2.mbn.or.jp).
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