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Exogenous Endophthalmitis Caused by Amphotericin BResistant Paecilomyces lilacinus: Treatment Options and Visual Outcomes
Arch Ophthalmol. 2001;119:916-919.
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INTRODUCTION
Paecilomyces lilacinus, an uncommon cause of exogenous endophthalmitis, presents a challenging management problem since the organism is usually resistant to amphotericin B, the most commonly employed intravitreal antifungal, and natamycin, a frequently employed topical antifungal. The organism is sensitive to miconazole nitrate, ketoconazole, and, in some cases, fluconazole. We report 4 cases of endophthalmitis caused by P lilacinus and discuss treatment options.
Report of Cases
Case 1
A 37-year-old man with hand motion vision in the left eye underwent penetrating keratoplasty, extracapsular cataract extraction, and posterior chamber intraocular lens implantation in the left eye 4 years after a bilateral ammonia chemical injury that resulted in persistent keratitis and corneal thinning. One day postkeratoplasty, he underwent wound leak repair. Examination 3 weeks later demonstrated a best-corrected visual acuity of 2/200 OS and a white flocculent mass on the cornea extending into the anterior chamber (Figure 1). After aqueous and vitreous specimens demonstrated filamentous . . . [Full Text of this Article] Case 2 Case 3 Case 4
Comment
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