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Hydroxyapatite Formation on Implanted Hydrogel Intraocular Lenses
Arch Ophthalmol. 2001;119:611-614.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Three Chinese patients undergoing implantation with the same hydrogel
intraocular lens (IOL)(Hydroview; Bausch & Lomb Surgical, Claremont, Calif)
developed delayed IOL opacification with unusual clinical features. The IOLs
were made from a 2-hydroxyethylmethacrylate/6-hydroxyhexylmethacrylate (HEMA/HOHEXMA)
copolymer. Opacification was progressive, whitish, and generalized, and developed
4 to 15 months after surgery. The appearance resembled a mature cataract.
All 3 patients showed a significant reduction in vision. There was no response
to Nd:YAG laser treatment, and all 3 IOLs had to be explanted. The explanted
lenses were analyzed with electron microscopy, elemental analysis, Fourier
Transform (FT) Raman spectroscopy, and x-ray diffraction to define the nature
of the opaque material. Results showed electron-dense deposits in the superficial
5 µm of the lenses. The deposits were predominantly composed of calcium
and phosphorus, and x-ray diffraction identified the presence of hydroxyapatite.
The polymer structure of the lens was unaltered.
Report of Cases
Case 1
A 67-year-old man underwent phacoemulsification on his . . . [Full Text of this Article] Case 2 Case 3 Methods
Results
Comment
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