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Ocular Management of Harlequin Syndrome
Chung N. Chua, MRCP, FRCOphth
Reading, England
J. Ainsworth, MBBS, FRCOphth
Birmingham, England
Arch Ophthalmol. 2001;119:454-455.
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A FEMALE infant, the first of dizygotic twins, was born at 32 weeks'
gestation to a gravida 1, 20-year-old mother. One twin was normal but the
other's clinical appearance was striking (Figure 1). The skin was hard, thickened, and split irregularly to
reveal erythematous moist fissures. There was severe ectropion of all 4 eyelids.
The external ears were rudimentary and the mouth showed eclabia causing a
characteristic "fish-mouth" appearance.
Figure appears in full text version.
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Figure 1. Facial appearance at birth.
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She was transferred to the neonatal intensive care unit and nursed in
a humidified incubator. Her body temperature was constantly monitored owing
to the risk of hypothermia. The eyes received hourly lubricant ointment.
At the age of 40 weeks, she developed a left corneal abscess caused
by methicillin-resistant Staphylococus aureus. The
eye responded well to hourly topical gentamicin eyedrops. During the next
2 . . . [Full Text of this Article] COMMENT
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ABSTRACT
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