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Evidence for the Role of Sunlight Exposure in the Etiology of Choroidal Melanoma
Arch Ophthalmol. 2001;119(3):430-431.
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CANCER RESEARCH
Patterns of Tumor Initiation in Choroidal Melanoma
Wenjun Li; Heidi Judge; Evangelos S. Gragoudas; Johanna M. Seddon; Kathleen M. Egan
This study attempts to document the occurrence of tumors with respect to clock hour location and distance from the macula and to evaluate tumor location in relation to retinal topography and light dose distribution on the retinal sphere. Analysis of patterns of tumor initiation may provide new evidence to clarify the controversy regarding the possible light-related etiology of choroidal melanoma. Incident cases of choroidal and ciliary body melanoma in Massachusetts residents diagnosed between 1984 and 1993 were the basis for analysis. Conventional fundus drawings and photos were used to assess the initiation site of each tumor. The initiation site was defined as the intersect between the largest tumor diameter and the largest perpendicular diameter of the tumor. Initiation sites were recorded using spherical coordinates. The retinal sphere was . . . [Full Text of this Article]
Claudia S. Moy, PhD
Baltimore, Md
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