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Arch Ophthalmol. 2001;119:298-300.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Stevens-Johnson syndrome (SJS), also known as the erythema multiform, is an acute, self-limited, inflammatory disorder of the skin and mucous membranes. Although the skin lesions are self-limited, the ocular disease gets worse and often results in bilateral blindness owing to a lack of corneal stem cells,¹ corneal scarring, and subconjunctival fibrosis. Prognosis of corneal transplantation in the acute phase is poor because of the difficulty of overcoming the severe inflammation and allograft rejection. Even in the chronic phase, it is difficult to control persistent inflammation, dry eye, and trichiasis, which induce persistent epithelial defect and allograft rejection. Although corneal stem cell transplantation and amniotic membrane (AM) transplantation, combined with dry eye treatment and strong immunosuppressive therapy, have been attempted at the scarring stage,² the management is difficult, and the visual prognosis is not satisfactory. However, if it were possible to control the severe inflammation and manage the corneal transplantation in . . . [Full Text of this Article]

Report of Cases


Comment
Corresponding author and reprints: Shigeru Kinoshita MD, PhD, Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kawaramachi-hirokoji, Kamigyo-ku, Kyoto 602-0841, Japan (e-mail: skinoshi@ophth.kpu-m.ac.jp).

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