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Arch Ophthalmol. 2001;119:1723-1725.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Late-onset bleb-related endophthalmitis is a potentially disastrous complication of trabeculectomy that may occur months to years after surgery. The route of infection is believed to involve migration of bacteria across the conjunctiva, in contrast to early postoperative endophthalmitis, which results from intraocular inoculation of microorganisms at the time of surgery.¹ Late-onset bleb-related infection occurs more frequently following full-thickness procedures, adjunctive antifibrosis chemotherapy, or when a late-onset bleb leak is present.²

The disease spectrum ranges from infection limited to the bleb to frank endophthalmitis.³ We present a case of panophthalmitis and orbital abscess, which occurred as a late-onset complication of trabeculectomy with adjunctive 5-fluorouracil (5-FU).

Report of a Case

A 69-year-old man had bilateral posterior chamber pseudophakia and a failed trabeculectomy in his right eye, and a thin-walled, avascular conjunctival filtering bleb in his left eye. He developed pain, redness, and discharge in his left eye while vacationing in another country. Examination by a local . . . [Full Text of this Article]

Comment

Reprints: Robert Ritch, MD, Glaucoma Service, Department of Ophthalmology, The New York Eye and Ear Infirmary, 310 E 14th St, New York, NY 10003 (e-mail: ritch@inx.net).

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