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Arch Ophthalmol. 2001;119:1716-1719.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Mastocytosis is a condition characterized by the presence of excessive numbers of tissue mast cells in distinctive distributions, which produce symptoms related to mast cell mediator release and the disruption of normal tissue function. To the best of our knowledge, mastocytosis with ocular and orbital involvement has not been previously documented. We describe a 42-year-old white man with biopsy-proven mastocytosis and multiple disseminated lesions who developed a reduction in visual acuity to counting fingers OS, an elevated choroidal mass in the macula, and bilateral orbital tumors.

Report of a Case

A 42-year-old non-Hispanic white man was diagnosed as having mastocytosis in 1996 after a bone marrow biopsy. He had a 1-year history of recurrent episodes of flushing, chest tightness, headache, and fever and on examination was noted to have lymphadenopathy and hepatosplenomegaly. No dermatologic lesions were present.

He subsequently developed an extramedullary mass lesion in thoracic vertebrae 2 through 8, which was compressing the . . . [Full Text of this Article]

Comment

Corresponding author: Michael R. Robinson, MD, National Eye Institute, National Institutes of Health, Bldg 10/Room 10N112, 10 Center Dr, Bethesda, MD 20892-1863 (e-mail: mrobin@box-m.nih.gov).

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