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Bilateral Combined Occlusion of the Central Retinal Artery and Vein Secondary to Thrombotic Thrombocytopenic Purpura
Stephen G. Schwartz, MD;
Alice R. McPherson, MD;
William F. Mieler, MD;
Sandra L. Sessoms, MD;
Joel L. Moake, MD;
Eric R. Holz, MD
Houston, Tex
Arch Ophthalmol. 2000;118:1304-1305.
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A HEALTHY 28-year-old Pakistani woman developed fever, malaise, and diffuse edema, rapidly progressing to multiple organ failure with encephalopathy, anuric renal failure, hemolytic anemia, and thrombocytopenia. The patient was diagnosed with thrombotic thrombocytopenic purpura (TTP) and treated with hemodialysis, intravenous corticosteroids, and plasma exchange with cryoprecipitate-poor plasma. After 2 weeks, her mental status improved, but she complained of bilateral vision loss.
Visual acuity was light perception in both eyes. Examination revealed bilateral vascular compromise with sheathing, cotton-wool spots, intraretinal hemorrhages, and optic disc pallor (Figure 1). Fluorescein angiography was significant for profound nonperfusion of retinal circulation (Figure 2).
Figure appears in full text version.
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Figure 1. Vascular compromise with sheathing, cotton-wool spots, intraretinal hemorrhages, and optic disc pallor. Left, right eye; right, left eye.
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Figure appears in full text version.
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COMMENT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Combined Occlusion of the Central Retinal Artery and Vein in a Pediatric Patient Secondary to Infective Endocarditis
Kato et al.
Arch Ophthalmol 2001;119:1868-1869.
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