JAMA
Acute Onset of Decreased Vision and Hearing Traced to Hemodialysis Treatment With Aged Dialyzers
Joseph C. Hutter, PhD; Matthew J. Kuehnert, MD; Roland R. Wallis, PhD; Anne D. Lucas, PhD; Sumit Sen, PhD; William R. Jarvis, MD
Context A recent event in which 7 patients at 1 hospital developed decreased vision and hearing, conjunctivitis, headache, and other severe neurologic symptoms 7 to 24 hours after hemodialysis drew attention to the issue of the long-term integrity of dialysis machines and materials.
Objective To determine the cause of the adverse reactions that occurred during this event.
Design, Patients, and Setting Retrospective cohort study of all 9 patients who received hemodialysis at hospital A on September 18, 1996, the day of the outbreak. A case-patient was defined as any hospital A patient with acute onset of decreased vision and hearing and conjunctivitis after dialysis on that day. Non–case-patients were all others who . . . [Full Text of this Article]