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Arch Ophthalmol. 2000;118:1133-1134.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Intense local cell reactions to silicone implants, gels, and oils have been described in various human tissues. Several articles have described histopathologically reactions to long-standing silicone oil in the human eye and the migration of silicone vacuoles into various ocular tissues.^1-2 However, to our knowledge, only 1 previous article described an intraocular giant cell reaction,³ and none have described a granulomatous reaction to intraocular silicone. We report a case in which an extensive granulomatous reaction to intraocular silicone oil was associated with enhanced serum IgG binding to silicones.

Report of a Case

A 50-year-old man with a history of cirrhosis secondary to alcoholic liver disease but an otherwise unremarkable medical and ophthalmic history was referred for the treatment of floaters and decreased vision in his right eye. The patient's visual acuity on initial examination was 20/200 OD, and findings from funduscopic examination revealed a small, yellow, parafoveal retinal lesion with a satellite lesion adjacent . . . [Full Text of this Article]

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Saad Shaikh, MD; Peter R. Egbert, MD; Randall S. Goldblum, MD; Mark R. Wieland, MD
Stanford, Calif

Corresponding author: Saad Shaikh, MD, Department of Ophthalmology, Stanford, Stanford University School of Medicine, CA 94305 (e-mail: saads@earthlink.net).
Reprints: Peter R. Egbert, MD, Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA 94305.

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