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What Can We Expect in Neuro-ophthalmology in the Next Century?
Simmons Lessell, MD
Arch Ophthalmol. 2000;118:553-554.
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Since it is quite unlikely that the advances made in neuro-ophthalmology could have been foreseen 100 years ago, it would be hubris to predict what lies ahead in the next 100 years. It is safer to confine myself to what I hope will and will not happen.
The restoration of vision to patients condemned to neural blindness should be one of our goals in the 21st century. At the close of the 20th century, preliminary achievements in 3 areas of research permit us to be optimistic that this goal can be achieved. Research on neurotransmitters and apoptosis has suggested that there are pharmacological means by which the vitality of retinal ganglion cells might be sustained in the face of axonal injury. Such neuroprotective agents are already being tested in animal models. Neural regeneration is a second area of promising research. Mature neurons in the adult retino-geniculo-calcarine pathway . . . [Full Text of this Article]
From the Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston.
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