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Treatment of Conjunctival Mucosa-Associated Lymphoid Tissue Lymphoma With Intralesional Injection of Interferon Alfa-2b
Arch Ophthalmol. 2000;118:284-285.
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Conjunctival mucosa-associated lymphoid tissue (MALT) lymphomas are typically localized, low-grade tumors that differ histologically from other forms of primary extranodal non-Hodgkin lymphomas. Patients with conjunctival MALT lymphoma have been cared for with radiation, chemotherapy, surgical excision, cryotherapy, and even observation alone. To our knowledge, this is only the third report of conjunctival MALT lymphoma treated with local injection of interferon alfa-2b (IFN- -2b)1-2 and the first to appear in the North American ophthalmic literature.
Report of a Case
A 21-year-old male student had a 2-month history of a painless, progressively enlarging mass on his right eye. Findings from anterior segment examination revealed a large salmon-colored lesion involving the right nasal conjunctiva, caruncle, and superior and inferior fornices (Figure 1). His uncorrected visual acuity was 20/20 OU and findings from the remainder of the ocular examination were unremarkable. The patient was tentatively diagnosed as having a conjunctival lymphoid neoplasm, pending biopsy and orbital . . . [Full Text of this Article]
Comment
Kevin R. Lachapelle, MD;
Rajinder Rathee, MD;
Vladimir Kratky, MD;
David F. Dexter, MD
Kingston, Ontario
Corresponding author: Kevin Lachapelle, MD, Department of Ophthalmology, Queen's University, Kingston, Ontario, Canada K7L 3N6.
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