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Raj K. Maturi, MD; James C. Folk, MD; Brian Nichols, MD, PhD; Thomas T. Oetting, MD; Randy H. Kardon, MD, PhD
Iowa City, Iowa

Arch Ophthalmol. 1999;117:1262-1263.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A 45-YEAR-OLD woman with an 18-year history of rheumatoid arthritis had a recent onset of decreased central vision. She had been taking a daily dose of 400 mg of hydroxychloroquine (8.5 mg/kg per day) for 6 years (cumulative dose of 876 g). Corrected visual acuity was 20/50 OU. Ishihara plate test results were 2/15 OU. Fundus examination showed pigment mottling in the macula of both eyes (Figure 1). Fluorescein angiography showed window defects in a bull's-eye pattern in both eyes (Figure 2). Static perimetry with a red test object (Humphrey Field Analyzer 10-2; Humphrey Instruments Inc, San Leandro, Calif) showed deep central scotomas in both eyes (Figure 3). Standardized Ganzfeld electroretinography revealed normal photopic and scotopic voltage and latency. Flicker response was normal . . . [Full Text of this Article]

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Multifocal Electroretinographic Evaluation of Long-term Hydroxychloroquine Users
Maturi et al.
Arch Ophthalmol 2004;122:973-981.
ABSTRACT | FULL TEXT