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Branch Retinal Arteriolar Occlusion Associated With Familial Factor V Leiden Polymorphism and Positive Rheumatoid Factor
Arch Ophthalmol. 1999;117:971-973.
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We describe a 33-year-old woman who was seen for blurred vision of sudden onset in the right eye and was found to have a branch retinal arteriole occlusion associated with familial factor V Leiden polymorphism and rheumatoid factor positivity. Immunological screening results were positive only for rheumatoid factor, and screening for thrombophilia revealed factor V Leiden polymorphism. Family screening results for the factor V Leiden polymorphism were positive in the patient's mother, who had suffered thromboembolic episodes, and in 2 other siblings who are asymptomatic to date.
Report of a Case
A 33-year-old white woman sought care because of a 2-week history of painless, blurred central vision and an inability to focus with her right eye. There was no history of pain, trauma, weight loss, fever, night sweats, arthralgias, rash, neurologic symptoms, or any eye problems. She had suffered from migraines since the age of 21 for which she was treated with atenolol, and . . . [Full Text of this Article] Comment
Corresponding author: Sushma Dhar-Munshi, Department of Ophthalmology, Room 5.012, Lanesborough Wing, St George's Hospital, Blackshaw Road, London SW 17 0QT, England (e-mail: sunil@webleicester.com.uk).
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