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Subconjunctival Corticosteroid Injections for Nonnecrotizing Anterior Scleritis
Arch Ophthalmol. 1999;117:966-968.
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Scleritis is an uncommon clinical entity that is frequently resistant to standard forms of topical and systemic treatment. The use of subconjunctival injections of corticosteroids for treating noninfectious, nonnecrotizing anterior scleritis has been discouraged in the literature for several decades because of a presumed risk for scleral thinning and globe perforation.1-2 The first report opposing this advice was published in 19953 and described 20 patients receiving injections during a 5-year period. Most had beneficial responses, and none developed scleral thinning or perforation.
The senior author (F.S.B.) of this report has used subconjunctival steroids as primary therapy for anterior scleritis for 28 years and has not seen significant scleral thinning or perforation as a result of an injection. We present this small case series to add supportive documentation of the safety and benefits of subconjunctival steroids for anterior nonnecrotizing scleritis. Although our experience using this mode of therapy extends beyond the . . . [Full Text of this Article] Report of Cases
Group 1 (Patients Receiving 1 Injection With Intermediate-Term Follow-up [12-45 Months]) CASE 1 Group 2 (Patients Receiving Multiple Injections With Long-term Follow-up) CASE 2 CASE 3 Group 3 (Patients With Severe Visual Disability or Intolerance After Standard Systemic Therapy) CASE 4 Comment
Corresponding author: Frederick S. Brightbill, MD, Department of Ophthalmology and Visual Sciences, University of Wisconsin, 2870 University Ave, Suite 102, Madison, WI 53705.
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