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Corneal Toxicity Associated With Latanoprost
Arch Ophthalmol. 1999;117:539-540.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Latanoprost is a new topical prostaglandin analog used to lower intraocular pressure. Adverse effects reported with use of latanoprost include cystoid macular edema, anterior uveitis, choroidal effusions, facial rash, hyperpigmentation of eyelashes, and iris hyperpigmentation.1-2 We describe 4 patients who developed pseudodendrites during treatment with latanoprost.
Report of Cases.
Case 1.
A 77-year-old woman was referred to us with a suspected diagnosis of herpes simplex keratitis. Her ocular history was significant for bilateral diabetic retinopathy necessitating vitrectomies and retinal laser treatments, followed by glaucoma for which the patient was treated with levobunolol hydrochloride twice daily to both eyes. Treatment with latanoprost was then added to the right eye for intraocular pressure control. Three weeks after treatment with latanoprost, the patient experienced symptoms of pain and irritation secondary to a corneal abrasion in the right eye. The abrasion was treated with a bandage contact lens for 1 week, followed by preserved artificial tears and lubricating ointment . . . [Full Text of this Article] Case 2. Case 3. Case 4. Comment.
Corresponding author: Sudha Sudesh, FRCOphth, Cornea Service, Wills Eye Hospital, 900 Walnut St, Philadelphia PA 19107.
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