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Arch Ophthalmol. 1999;117:1650-1653.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Neurofibromatosis type 2 (NF2), previously known as central neurofibromatosis, is defined clinically by the presence of bilateral acoustic nerve schwannomas and genetically by a mutation in the long arm of chromosome 22.¹ Schwannomas of other cranial and spinal nerves are often present, as well as meningiomas. Patients typically have hearing loss in the second or third decade of life. About 50% of cases are inherited in an autosomal dominant fashion.

Among the many ophthalmic signs that have been described in NF2,^1-4 papilledema has not been highlighted. We report 2 cases in which the dire consequences of sustained elevated intracranial pressures were not recognized in time to prevent visual loss.

Report of Cases

Case 1

A 31-year-old man reported a 2-year history of worsening bilateral hearing loss and dizziness in 1992. Bilateral sensorineural hearing was documented. Results of a neurological examination were otherwise normal. A magnetic resonance imaging (MRI) scan disclosed masses coating the cerebral convexities . . . [Full Text of this Article]

Case 2

Comment
Reprints: Jonathan D. Trobe, MD, W. K. Kellogg Eye Center, 1000 Wall St, Ann Arbor, MI 48105 (e-mail: jdtrobe@umich.edu).

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