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Arch Ophthalmol. 1999;117:1646-1647.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Several prostaglandins have been demonstrated to reduce intraocular pressure (IOP) in normal, hypertensive, and glaucomatous eyes.^1-3 Two different prostaglandin analogs are commercially available: unoprostone (Rescula; Ciba Vision Ophthalmics, Duluth, Ga) and latanoprost (Xalatan; Pharmacia Inc, Columbus, Ohio). We observed an inverse reaction after topical administration of both analogs.

Report of a Case

A 29-year-old woman had retinitis pigmentosa with typical ophthalmoscopic findings, a ring scotoma, and a flat electroretinogram. Juvenile glaucoma was diagnosed at the age of 12 years. Because of the characteristic malformation of the anterior segment it was classified as Rieger syndrome. The initial IOP at the time of glaucoma detection was 50 mm Hg. Both eyes underwent Elliot operation. The left eye required an additional cryocoagulation of the ciliary body. After these operations, the IOP of the right eye was between 8 and 14 mm Hg without further medication. The IOP of the left eye was below 21 mm Hg until . . . [Full Text of this Article]

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Corresponding author: Thomas Ness, MD, Universitäts-Augenklinik Freiburg, Killianstr. 5, D-79106 Freiburg, Germany.