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Cardiac Metastasis of Choroidal Melanoma
Arch Ophthalmol. 1999;117:1558-1559.
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We report a rare occurrence of cardiac metastasis from uveal melanoma.
Report of a Case
A 74-year-old woman had decreased vision in the left eye. On examination, she was found to have a pigmented choroidal lesion in the superior fundus that measured 11 x 11 mm at the base and 6.2 mm in height. The diagnosis was a medium-sized choroidal melanoma (Figure 1). The patient entered the Collaborative Ocular Melanoma Study and received sodium iodide I 125 brachytherapy in October 1987. Eight years and 9 months later, the patient complained of dizziness, was examined, and was found to have a left ventricular mass (Figure 2). She underwent an excisional biopsy, but died the following day of a ruptured myocardium. Microscopic examination of the excised tissue revealed pigmented cells invading the myocardium consistent with metastatic choroidal melanoma (Figure 3).
Figure appears in full text version.
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Figure 1. Left fundus photograph of a medium-sized choroidal melanoma.
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Figure appears in full text version.
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Comment Corresponding author: Daniel M. Albert, MD, MS, Department of Ophthalmology and Visual Sciences, University of WisconsinMadison Medical School, F4/336 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3220 (e-mail: albert@eyesee.ophth.wisc.edu).
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