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Arch Ophthalmol. 1998;116:1106-1107.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

ALL OPHTHALMOLOGISTS who deal with patients who have Graves ophthalmopathy should read the landmark article titled "Relation Between Therapy for Hyperthyroidism and the Course of Graves' Ophthalmopathy" by Bartalena et al¹ and also the accompanying excellent editorial by Wiersinga.²

In the study by Bartalena and coworkers, evidence is presented that radioiodine alone may promote or worsen existing Graves ophthalmopathy in patients with Graves hyperthyroidism. Bartalena and coworkers conclude that radioiodine is followed by worsening of Graves ophthalmopathy in 15% of the patients treated with radioiodine, but none of those treated with radioiodine and prednisone and only 3% of those treated with methimazole experienced any worsening of eye disease.

However, there are some issues that need to be emphasized. Of the 150 patients treated with radioiodine, the ophthalmopathy developed or worsened in 23 (15%) 2 to 6 months after treatment. The changes were transient in 15 patients but persisted in 8 . . . [Full Text of this Article]

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