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A Welcome New Idea for the Management of Adenocystic Carcinoma of the Lacrimal Gland

Arch Ophthalmol. 1998;116:372-373.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

ADENOCYSTIC CARCINOMA is an aggressive disease with a propensity for perineural, hematogenous, and lymphatic invasion. The prognosis is grim: approximately 70% to 80% of patients succumb to the disease within 10 years of diagnosis despite aggressive and often disfiguring treatment, and recurrences can occur 15 or 20 years after excision, making true cures extremely rare.^1-2

Radical orbitectomy for adenoid cystic carcinoma is advocated by many orbital specialists. This disfiguring operation involves removing the orbital contents en bloc along with various amounts of orbital bone.^3-4 More recent publications have recommended eye-sparing procedures.^4-5 Comparison of survival rates for radical vs eye-sparing procedures has failed to demonstrate improved survival with more radical surgery.^1-5 Complete surgical excision of adenocystic carcinoma of the lacrimal gland is difficult to achieve even with radical surgery. In fact, the most common site of recurrence of adenocystic carcinoma of the lacrimal gland is local.¹ Complex regional anatomy, an infiltrative . . . [Full Text of this Article]

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