Cyclosporine-Induced Resolution of Choroidal Neovascularization Associated With Sympathetic Ophthalmia
Arch Ophthalmol. 1998;116:249-250.
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Choroidal neovascularization (CNV) is a sight-threatening complication of sympathetic ophthalmia, a classic example of endogenous posterior uveitis.1,2Cyclosporine (cyclosporin A) has been shown to be effective in the treatment of sight-threatening disease associated with active intraocular inflammation in adults.3 We present a case report illustrating resolution of CNV in a child with active refractory sympathetic ophthalmia after starting cyclosporine therapy.
Report of a Case
A 3-year-old boy had a limbal rupture involving uveal prolapse of his right eye after he fell on his feeder cup. Primary repair was performed and postoperative visual acuity was 20/80 OD and 20/20 OS. When sympathetic ophthalmia developed 4 months later, his visual acuity deteriorated to finger counting in both eyes. Oral prednisone therapy at 1 mg/kg per day was started. His uveitis improved slowly; 1 year later he achieved a visual acuity of finger counting OD and 20/30 OS while receiving a maintenance dose of 1 mg/kg on . . . [Full Text of this Article]
Comment
Dara J. Kilmartin, FRCOphth;
John V. Forrester, MD;
Andrew D. Dick, MD
Aberdeen, Scotland
Reprints: Dara J. Kilmartin, FRCOphth, University of Aberdeen Medical School, Foresterhill, Aberdeen AB25 2ZD, Scotland (e-mail: d.j.kilmartin@abdn.ac.uk).
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